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Pancreatic cancer, particularly pancreatic ductal adenocarcinoma (PDAC), is a highly lethal malignancy with unclear causes. However, certain risk factors increase the likelihood of its development:
ā¢ Genetic factors: Family history of pancreatic cancer or certain genetic mutations (e.g., BRCA1, BRCA2, p16, Lynch syndrome) can increase the risk.
ā¢ Smoking: Tobacco use is one of the major preventable causes.
ā¢ Chronic Pancreatitis: Long-term inflammation of the pancreas, especially due to alcohol use, can increase the risk.
ā¢ Diabetes: Long-standing type 2 diabetes has been associated with a higher risk.
ā¢ Obesity and poor diet: High-fat diets and obesity are linked to an increased incidence of pancreatic cancer.
#pancreas
#cancer
#surgeryreview
Professor Armen Astvatsatryan, MD, PhD, ScD, Fellow of European Society of Cardiology. First Dean and Founder of Faculty of Public Health of European Regional Educational Academy (now University). One of 100 Top Health Professionals - 2007 by the International Biographical Center`s (Cambridge, England)
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