Woman on the Run (1950) Ann Sheridan and Dennis O’Keefe

A murder witness runs from the murderer out to kill him; and, through the ordeal, a couple mend their film title is actually misleading, as it is a man, not a woman, who is the one on the run. The story takes place in San Francisco. Frank Johnson is an artist who is out walking his dog one night and happens to witness, from a slight distance, a gangland slaying when a car stops nearby. The passenger, Joe, threatens to extort the driver, Danny, seeking additional money for his favorable grand jury testimony. As Frank watches, Danny fires a gun into Joe and keeps shooting even after Joe falls dead out the car door. Noticing Frank, Danny takes shots at him. A neighbor calls police who arrive. Inspector Ferris learns that Frank, the sole witness, could definitely identify the killer in a lineup and detains Frank to be put into protective custody. But, although cooperative, looking at the bullet holes in the chest area of his shadow on a nearby wall -- whether because of, or in spite of, having a heart condition, Frank soon panics and escapes on the run.