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Penicillin | Antibiotics | Dr Najeeb | Part 2/4
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(0:00-3:25)
Outline: Cell wall synthesis inhibitors: Cycloserine, Bacitracin, Vancomycin, Beta Lactam drugs: Penicillins, Cephalosporins, Carbapenem, Aztreonam
(3:29-10:05)
Bacterial Cell Wall; Gram ve and Gram -ve; comparison of structure.
(10:15:14:48)
MOA Beta Lactam drugs; Penicillin Binding Proteins (PBP), Porins in Gram -ve.
(14:50-22:54)
Wide spectrum and Narrow spectrum Penicillins; Natural Penicillins : Pen G and V; Spirochetes : Treponema Pallidum and Borrelia Burgdorferi
(22:58-34:36)
Very Very Narrow Spectrum Penicillins ; Antistaphylococcal Penicillins: Methicillin, Nafcillin, Oxacillin, Dicloxacillin, Ofloxacillin; Penicillinase/Beta lactamases.
(34:40-44:08)
Penicillin G (IV) and Penicillin V (Oral); Beta-hemolyticus Streptococcus A : Rheumatic Fever. Methicillin Resistant Staphylococcus Aureus (MRSA).
(44:10-52:34)
Wide Spectrum Penicillin [extended to Gram -ve]: Ampicillin, Amoxicillin: Hemophilus Influenzae, , Listeria Monocytogenes, Proteus, Salmonella, Enterococci.
(52:36-58:45)
Ampicillin and Amoxicillin: Vulnerability to Gram -ve; Anti beta lactamases: Clavulanic Acid, Sulbactam, Tazobactam.
(58:47-1:07:28)
Anti-Pseudomonal Penicillins: Piperacillin, Ticarcillin, Carbenicillin. Pseudomonas Aeruginosa; Surgical Infections,
(1:07:33-1:10:02)
Summary
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